1281.25% is the change from 16 to 221
Calculation steps:
[( 221 - 16 ) ÷ 16] x 100 = 1281.25%
Formula
Percentage change = [(221 - 16) / 16] x 100
Subtract the new number by the original number
221 - 16 = 205
205 ÷ 16 = 12.8125
12.8125 x 100 = 1281.25%