3781.25% is the change from 16 to 621
Calculation steps:
[( 621 - 16 ) ÷ 16] x 100 = 3781.25%
Formula
Percentage change = [(621 - 16) / 16] x 100
Subtract the new number by the original number
621 - 16 = 605
605 ÷ 16 = 37.8125
37.8125 x 100 = 3781.25%