306.25% is the change from 16 to 65
Calculation steps:
[( 65 - 16 ) ÷ 16] x 100 = 306.25%
Formula
Percentage change = [(65 - 16) / 16] x 100
Subtract the new number by the original number
65 - 16 = 49
49 ÷ 16 = 3.0625
3.0625 x 100 = 306.25%
Example