-33.49% is the change from 421 to 280
Calculation steps:
[( 280 - 421 ) ÷ 421] x 100 = -33.49%
Formula
Percentage change = [(280 - 421) / 421] x 100
Subtract the new number by the original number
280 - 421 = -141
-141 ÷ 421 = -0.334916864608076
-0.334916864608076 x 100 = -33.49%