42.76% is the change from 421 to 601
Calculation steps:
[( 601 - 421 ) ÷ 421] x 100 = 42.76%
Formula
Percentage change = [(601 - 421) / 421] x 100
Subtract the new number by the original number
601 - 421 = 180
180 ÷ 421 = 0.42755344418052255
0.42755344418052255 x 100 = 42.76%