52.73% is the change from 421 to 643
Calculation steps:
[( 643 - 421 ) ÷ 421] x 100 = 52.73%
Formula
Percentage change = [(643 - 421) / 421] x 100
Subtract the new number by the original number
643 - 421 = 222
222 ÷ 421 = 0.5273159144893111
0.5273159144893111 x 100 = 52.73%