53.21% is the change from 421 to 645
Calculation steps:
[( 645 - 421 ) ÷ 421] x 100 = 53.21%
Formula
Percentage change = [(645 - 421) / 421] x 100
Subtract the new number by the original number
645 - 421 = 224
224 ÷ 421 = 0.5320665083135392
0.5320665083135392 x 100 = 53.21%