-6.53% is the change from 643 to 601
Calculation steps:
[( 601 - 643 ) ÷ 643] x 100 = -6.53%
Formula
Percentage change = [(601 - 643) / 643] x 100
Subtract the new number by the original number
601 - 643 = -42
-42 ÷ 643 = -0.06531881804043546
-0.06531881804043546 x 100 = -6.53%