-41.61% is the change from 721 to 421
Calculation steps:
[( 421 - 721 ) ÷ 721] x 100 = -41.61%
Formula
Percentage change = [(421 - 721) / 721] x 100
Subtract the new number by the original number
421 - 721 = -300
-300 ÷ 721 = -0.4160887656033287
-0.4160887656033287 x 100 = -41.61%